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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STK39
All Species:
14.24
Human Site:
Y446
Identified Species:
26.11
UniProt:
Q9UEW8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UEW8
NP_037365.2
547
59642
Y446
P
P
N
A
N
E
D
Y
R
E
A
S
S
C
A
Chimpanzee
Pan troglodytes
XP_515880
720
78003
Y619
P
P
N
A
N
E
D
Y
R
E
A
S
S
C
A
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
E400
P
S
F
L
E
Y
F
E
Q
K
E
K
E
N
Q
Dog
Lupus familis
XP_535944
666
73491
Y566
L
P
N
A
S
E
D
Y
R
E
T
S
C
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1W9
556
60301
Y456
Q
P
N
A
N
E
D
Y
R
E
G
P
C
A
V
Rat
Rattus norvegicus
O88506
553
60032
Y453
Q
P
N
A
N
E
D
Y
R
E
G
P
C
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513780
525
58469
F425
Q
H
N
V
S
E
E
F
T
E
A
S
C
A
V
Chicken
Gallus gallus
XP_422019
453
50652
L366
E
V
P
C
A
V
N
L
V
L
R
L
R
N
S
Frog
Xenopus laevis
Q6PA14
485
55246
E398
Q
A
K
P
S
F
L
E
Y
F
E
Q
K
E
N
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
S404
D
Y
F
D
K
Q
D
S
N
K
A
Q
E
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477308
552
60283
E450
A
Q
L
P
L
P
S
E
A
A
G
E
A
P
P
Honey Bee
Apis mellifera
XP_396480
690
76398
V599
P
S
I
P
I
N
L
V
L
R
L
R
N
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791076
537
59936
D437
G
E
T
E
Q
I
S
D
G
G
D
Q
T
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
27.4
73.5
N.A.
96
96.3
N.A.
89.7
79.8
27.9
28.3
N.A.
56.8
47.3
N.A.
54.3
Protein Similarity:
100
75
45.1
76.5
N.A.
96.4
96.9
N.A.
92.3
81.5
46.2
45.3
N.A.
71.7
59.1
N.A.
71.6
P-Site Identity:
100
100
6.6
60
N.A.
60
60
N.A.
33.3
0
0
13.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
20
66.6
N.A.
60
60
N.A.
53.3
13.3
6.6
26.6
N.A.
6.6
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
39
8
0
0
0
8
8
31
0
8
31
16
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
31
16
0
% C
% Asp:
8
0
0
8
0
0
47
8
0
0
8
0
0
0
0
% D
% Glu:
8
8
0
8
8
47
8
24
0
47
16
8
16
8
0
% E
% Phe:
0
0
16
0
0
8
8
8
0
8
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
8
8
24
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
0
16
0
8
8
0
8
% K
% Leu:
8
0
8
8
8
0
16
8
8
8
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
47
0
31
8
8
0
8
0
0
0
8
16
8
% N
% Pro:
31
39
8
24
0
8
0
0
0
0
0
16
0
16
16
% P
% Gln:
31
8
0
0
8
8
0
0
8
0
0
24
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
39
8
8
8
8
0
0
% R
% Ser:
0
16
0
0
24
0
16
8
0
0
0
31
16
0
8
% S
% Thr:
0
0
8
0
0
0
0
0
8
0
8
0
8
0
0
% T
% Val:
0
8
0
8
0
8
0
8
8
0
0
0
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
39
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _